Recruitment of LC3 to damaged Golgi apparatus
نویسندگان
چکیده
منابع مشابه
Positioning the Golgi Apparatus
Ríos et al. (2004) report in this issue that the Golgi protein GMAP-210 is sufficient to confer pericentrosomal positioning and recruits gamma-tubulin and associated microtubule-nucleating ring complex proteins to Golgi membranes. The results raise the possibility that short microtubules emanate from the Golgi to mediate its organization and positioning.
متن کاملThe Golgi apparatus
At some point in their lives all cells need to grow and divide. In eukaryotic cells these processes require the delivery of new proteins and lipids from their site of synthesis in the endoplasmic reticulum (ER) to the cell surface. The Golgi apparatus, first visualised under the light microscope in 1898 by Camillo Golgi using a staining method he had developed to study neurons, lies on the rout...
متن کاملGolgi Apparatus of Rat Kidney
A procedure has been developed for the isolation of morphologically recognizable, largely intact, Golgi apparatus from rat kidneys. The fraction contains both uridine diphosphogalactose: IVacetylglucosamine galactosyltransferase and 3’-phosphoadenosine 5’-phosphosulfate: cerebroside sulfotransferase activities enriched 50to 80-fold over the original homogenate. Comparison of the Golgi-rich frac...
متن کاملGolgi Apparatus of Rat Kidney
A procedure has been developed for the isolation of morphologically recognizable, largely intact, Golgi apparatus from rat kidneys. The fraction contains both uridine diphosphogalactose: IVacetylglucosamine galactosyltransferase and 3’-phosphoadenosine 5’-phosphosulfate: cerebroside sulfotransferase activities enriched 50to 80-fold over the original homogenate. Comparison of the Golgi-rich frac...
متن کاملFragmentation of the Golgi Apparatus
Phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) synthesis has been implicated in maintaining the function of the Golgi apparatus. Here we demonstrate that the inhibition of PtdIns(4,5)P2 synthesis in vitro in response to primary alcohol treatment and the kinetics of Golgi fragmentation in vivo were very rapid and tightly coupled. Preloading Golgi membranes with short chain phosphatidic ac...
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ژورنال
عنوان ژورنال: Cell Death & Differentiation
سال: 2018
ISSN: 1350-9047,1476-5403
DOI: 10.1038/s41418-018-0221-5